COVID-19 Research Paper Volume 13, Issue 12 pp 15785—15800

Clinical characterization and therapeutic targets of vitamin A in patients with hepatocholangiocarcinoma and coronavirus disease

Identification and functional characterization of CHOL/COVID-19/Vitamin A-associated genes. (A) Venn diagram showed the number of intersecting genes of vitamin A and CHOL/COVID-19. (B) Gene ontology enrichment analysis highlighted the biological processes affected by the VA/CHOL/COVID-19-associated genes. (C) The bubble diagram showed the involvement of genes in different biological processes. (D) Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis demonstrated the alteration of cell signaling pathways by the VA/CHOL/COVID-19-associated genes. (E) The bubble diagram showed the involvement of genes in different cell signaling pathways. (F) Interaction network showed core biotargets, pharmacological functions, and signaling pathways of VA against CHOL/COVID-19.VA.

Figure 3. Identification and functional characterization of CHOL/COVID-19/Vitamin A-associated genes. (A) Venn diagram showed the number of intersecting genes of vitamin A and CHOL/COVID-19. (B) Gene ontology enrichment analysis highlighted the biological processes affected by the VA/CHOL/COVID-19-associated genes. (C) The bubble diagram showed the involvement of genes in different biological processes. (D) Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis demonstrated the alteration of cell signaling pathways by the VA/CHOL/COVID-19-associated genes. (E) The bubble diagram showed the involvement of genes in different cell signaling pathways. (F) Interaction network showed core biotargets, pharmacological functions, and signaling pathways of VA against CHOL/COVID-19.VA.