Research Paper Volume 13, Issue 12 pp 16816—16833

Celastrol protects against early brain injury after subarachnoid hemorrhage in rats through alleviating blood-brain barrier disruption and blocking necroptosis

Neurological subscores at 24, 48 and 72h after SAH induction. (A–F) Subscores of (A) spontaneous activity, (B) symmetry in limb movement, (C) forepaw outstretching, (D) climbing, (E) response to touch on either side of trunk, (F) response to vibrissae at each time point after SAH. Data were presented as mean±SEM. n = 14. *P

Figure 2. Neurological subscores at 24, 48 and 72h after SAH induction. (AF) Subscores of (A) spontaneous activity, (B) symmetry in limb movement, (C) forepaw outstretching, (D) climbing, (E) response to touch on either side of trunk, (F) response to vibrissae at each time point after SAH. Data were presented as mean±SEM. n = 14. *P < 0.05 versus sham, **P < 0.01 versus sham, #P < 0.05 versus SAH + vehicle.