Research Paper Volume 13, Issue 12 pp 16816—16833

Celastrol protects against early brain injury after subarachnoid hemorrhage in rats through alleviating blood-brain barrier disruption and blocking necroptosis

Effect of celastrol treatment on MMP-9 expression at 72 h after SAH induction. (A) Representative WB showing levels of MMP-9 in the ipsilateral cortex of each group at 72 h after SAH induction. (B) Quantifications of band densities of MMP-9. The densities of the protein bands were analyzed and normalized to β-actin, and compared to the mean value of the sham group. Data were presented as mean±SEM. n = 6. **P

Figure 6. Effect of celastrol treatment on MMP-9 expression at 72 h after SAH induction. (A) Representative WB showing levels of MMP-9 in the ipsilateral cortex of each group at 72 h after SAH induction. (B) Quantifications of band densities of MMP-9. The densities of the protein bands were analyzed and normalized to β-actin, and compared to the mean value of the sham group. Data were presented as mean±SEM. n = 6. **P < 0.01.