Research Paper Volume 13, Issue 12 pp 16816—16833

Celastrol protects against early brain injury after subarachnoid hemorrhage in rats through alleviating blood-brain barrier disruption and blocking necroptosis

Effects of celastrol on cell injury in the ipsilateral basal cortex at 72 h after SAH induction. (A) Representative microphotographs showed the co-localization of DAPI (blue) with PI (red) positive cells in the ipsilateral basal cortex at 72 h after SAH induction. (B) Quantitative analysis of PI positive cells at 72 h after SAH induction. Data were presented as mean±SEM. n = 6. **P

Figure 9. Effects of celastrol on cell injury in the ipsilateral basal cortex at 72 h after SAH induction. (A) Representative microphotographs showed the co-localization of DAPI (blue) with PI (red) positive cells in the ipsilateral basal cortex at 72 h after SAH induction. (B) Quantitative analysis of PI positive cells at 72 h after SAH induction. Data were presented as mean±SEM. n = 6. **P < 0.01. Scale bar = 100 μm.