Review Volume 13, Issue 13 pp 17930—17947

Research progress of melatonin (MT) in improving ovarian function: a review of the current status

Antioxidant mechanism of MT in cells [7,53]. Abbreviations: MT, melatonin; ROS, reactive oxygen species; mtPTP, mitochondrial permeability transition pore; SOD, superoxide dismutase; Mn-SOD, Mn-superoxide dismutase; UCPs, uncoupling protein gene; HO-1, heme oygenase-1; Nrf-2, nuclear factor erythroid-2-related factor-2; GPx, utathione peroxidase; and NOS, nitric oxide synthase.

Figure 3. Antioxidant mechanism of MT in cells [7,53]. Abbreviations: MT, melatonin; ROS, reactive oxygen species; mtPTP, mitochondrial permeability transition pore; SOD, superoxide dismutase; Mn-SOD, Mn-superoxide dismutase; UCPs, uncoupling protein gene; HO-1, heme oygenase-1; Nrf-2, nuclear factor erythroid-2-related factor-2; GPx, utathione peroxidase; and NOS, nitric oxide synthase.