Research Paper Volume 13, Issue 13 pp 17462—17472

miR-30a-5p suppresses lung squamous cell carcinoma via ATG5 - mediated autophagy

The expression and prognosis of ATG5 in LUSC. (A) Survival curves of ATG5 expression for prognosis in the TCGA-LUSC dataset. Red represents high expression group and blue was for low expression; (B) Compare with normal group(blue), the expression of ATG5 was high in tumor samples (red) (C and D) Box plots of ATG5 expression in different clinical stages, N stages of LUSC; (E and F) mRNA and protein expressions of ATG5 in HPAEpic and LUSC cell lines (NCI-H1730, NCI-H2170, LOU-NH91 and SW900) All the P values were compared with the control *P **P ***P

Figure 1. The expression and prognosis of ATG5 in LUSC. (A) Survival curves of ATG5 expression for prognosis in the TCGA-LUSC dataset. Red represents high expression group and blue was for low expression; (B) Compare with normal group(blue), the expression of ATG5 was high in tumor samples (red) (C and D) Box plots of ATG5 expression in different clinical stages, N stages of LUSC; (E and F) mRNA and protein expressions of ATG5 in HPAEpic and LUSC cell lines (NCI-H1730, NCI-H2170, LOU-NH91 and SW900) All the P values were compared with the control *P < 0.05, **P < 0.01, ***P < 0.0001.