Research Paper Volume 13, Issue 13 pp 17489—17498

HDAC inhibitor Trichostatin A suppresses adipogenesis in 3T3-L1 preadipocytes

TSA promotes lipolysis during 3T3-L1 adipogenesis. Cells were incubated with differentiation cocktail (DMI) medium with TSA (0.5 and 1 μM). (A) Total level of triglyceride; (B) Lipolysis is shown as glycerol release (n=5-6, ##, ####, P

Figure 3. TSA promotes lipolysis during 3T3-L1 adipogenesis. Cells were incubated with differentiation cocktail (DMI) medium with TSA (0.5 and 1 μM). (A) Total level of triglyceride; (B) Lipolysis is shown as glycerol release (n=5-6, ##, ####, P<0.01, 0.0001, VS. vehicle group; &&, &&&, P<0.01, 0.001 vs. DMI treatment group).