Research Paper Volume 13, Issue 13 pp 17489—17498

HDAC inhibitor Trichostatin A suppresses adipogenesis in 3T3-L1 preadipocytes

TSA reduces the weight of visceral adipocyte tissue and the bodyweight of HFD-induced obese mice (10 weeks, start with 6-8 weeks old B6 male mice). (A) Bodyweight; (B) Histological sections of visceral adipocyte tissue; (C) Quantification of adipocyte size; (D) Visceral adipocyte tissue weight (n=5-6, ###, P

Figure 7. TSA reduces the weight of visceral adipocyte tissue and the bodyweight of HFD-induced obese mice (10 weeks, start with 6-8 weeks old B6 male mice). (A) Bodyweight; (B) Histological sections of visceral adipocyte tissue; (C) Quantification of adipocyte size; (D) Visceral adipocyte tissue weight (n=5-6, ###, P<0.001 vs. vehicle group; &, &&, P<0.05, 0.01 vs. HFD group).