Research Paper Volume 13, Issue 13 pp 17499—17515

Downregulation of LINC00665 suppresses the progression of lung adenocarcinoma via regulating miR-181c-5p/ZIC2 axis

Bioinformatics analysis of the expression and clinical value of LINC00665 in LUAD. (A) The expression patterns of LINC00665 in different kinds of cancers were identified using GEPIA software. (B) StarBase bioinformatics method was applied to analyze the different expression levels of LINC00665 in LUAD tissues and the normal samples. (C) TCGA database showed that high expression of LINC00665 predicted a poor prognosis in LUAD patients. (D) StarBase bioinformatics method was used to assess the relationship between miR-181c-5p expression levels of the overall survival in LUAD. (E) Venn image showing the genes which was not only upregulated in LUAD but also under the regulation of miR-181c-5p.

Figure 1. Bioinformatics analysis of the expression and clinical value of LINC00665 in LUAD. (A) The expression patterns of LINC00665 in different kinds of cancers were identified using GEPIA software. (B) StarBase bioinformatics method was applied to analyze the different expression levels of LINC00665 in LUAD tissues and the normal samples. (C) TCGA database showed that high expression of LINC00665 predicted a poor prognosis in LUAD patients. (D) StarBase bioinformatics method was used to assess the relationship between miR-181c-5p expression levels of the overall survival in LUAD. (E) Venn image showing the genes which was not only upregulated in LUAD but also under the regulation of miR-181c-5p.