Research Paper Volume 13, Issue 13 pp 17607—17628

Comprehensive analysis of an immune-related ceRNA network in identifying a novel lncRNA signature as a prognostic biomarker for hepatocellular carcinoma

GSEA. Hallmark enrichment analysis in this study revealed that the immune-related lncRNA signature in the high-risk group was primarily linked with (A) G2M checkpoint, (B) PI3K/AKT/MTOR signaling pathway, and (C) glycolysis. The immune-related lncRNA model also regulated immunologic signatures within the immune system, such as (D) Germinal center (GC) B cell vs. plasma cell up, (E) memory vs. naïve CD8 T cell down and (F) CD4 T cell vs. NK T cell down.

Figure 6. GSEA. Hallmark enrichment analysis in this study revealed that the immune-related lncRNA signature in the high-risk group was primarily linked with (A) G2M checkpoint, (B) PI3K/AKT/MTOR signaling pathway, and (C) glycolysis. The immune-related lncRNA model also regulated immunologic signatures within the immune system, such as (D) Germinal center (GC) B cell vs. plasma cell up, (E) memory vs. naïve CD8 T cell down and (F) CD4 T cell vs. NK T cell down.