Research Paper Volume 13, Issue 17 pp 21090—21101

Effect of the Notch1-mediated PI3K-Akt-mTOR pathway in human osteosarcoma

shNotch1 up-regulated the PI3K/Akt signaling pathway in human osteosarcoma cells. (A) The graphs of western blots were present. (B) Levels of PI3K, p-PI3K, Akt and p-Akt were analyzed by western blotting. *P

Figure 7. shNotch1 up-regulated the PI3K/Akt signaling pathway in human osteosarcoma cells. (A) The graphs of western blots were present. (B) Levels of PI3K, p-PI3K, Akt and p-Akt were analyzed by western blotting. *P<0.05, significantly different compared with the untreated control group. All the experiments were conducted in triplicates.