Research Paper Volume 13, Issue 13 pp 17734—17767

Clinical significance and prognostic role of an immune-related gene signature in gastric adenocarcinoma

Tumor somatic mutational landscape of the IBPS. (A) The top 35 gene mutations in the high-risk score group. (B) The top 35 gene mutations in the low-risk score group. (C, D) Mutations in the commonly mutated genes TP53, ERBB2, EGFR, FGFR2, MET, and KRAS in the high-risk and low-risk score groups, respectively. (E) Kaplan-Meier curves of OS in all GAC patients based on TMB. (F) Difference in TMB between the high- and low-risk groups. (G) Difference in risk scores between the high and low TMB groups.

Figure 6. Tumor somatic mutational landscape of the IBPS. (A) The top 35 gene mutations in the high-risk score group. (B) The top 35 gene mutations in the low-risk score group. (C, D) Mutations in the commonly mutated genes TP53, ERBB2, EGFR, FGFR2, MET, and KRAS in the high-risk and low-risk score groups, respectively. (E) Kaplan-Meier curves of OS in all GAC patients based on TMB. (F) Difference in TMB between the high- and low-risk groups. (G) Difference in risk scores between the high and low TMB groups.