Research Paper Advance Articles

Aberrant expression of WDR4 affects the clinical significance of cancer immunity in pan-cancer

WDR4 expression is correlated with cancer immunity. (A) TIMER predicts that the WDR4 level is related to the degree of immune infiltration within BRCA, CHOL and HNSC. (B) The heat map represents the relationship between 47 immune checkpoint genes and the gene expression of WDR4. For each pair, the right triangle is coloured to represent the P-value; the bottom left o is coloured to indicate the Spearman correlation coefficient. *P **P ***P C) Relationship between gene expression and the StromalScore, Est

Figure 7. WDR4 expression is correlated with cancer immunity. (A) TIMER predicts that the WDR4 level is related to the degree of immune infiltration within BRCA, CHOL and HNSC. (B) The heat map represents the relationship between 47 immune checkpoint genes and the gene expression of WDR4. For each pair, the right triangle is coloured to represent the P-value; the bottom left o is coloured to indicate the Spearman correlation coefficient. *P < .05; **P < .01; ***P < .001. (C) Relationship between gene expression and the StromalScore, Est_ImmuneScore and ESTIMATEScore.