Research Paper Volume 13, Issue 13 pp 17864β€”17879

A innovative prognostic symbol based on neutrophil extracellular traps (NETs)-related lncRNA signature in non-small-cell lung cancer

Identification and analyses of lncRNAs correlated with NETs. (A) Venn diagram identifying 119 overlapping NETs-related genes between TCGA and transcriptome RNA microarrays. (B) Forest plots demonstrating the results of the univariate Cox regression analysis between NETs-related lncRNA expression and overall survival (OS). (C) Heatmap revealing the NETs-related lncRNAs that were associated with OS by univariate Cox regression analysis in NSCLC patients and healthy people. (D) The coexpression network between 12 NETs-related lncRNAs and prognostic DEGs. Red indicates NETs-related lncRNA, and the purple indicates prognostic DEGs. (E) Sankey diagram showing the relationships among 12 NETs-related lncRNAs, prognostic DEGs and risk types.

Figure 3. Identification and analyses of lncRNAs correlated with NETs. (A) Venn diagram identifying 119 overlapping NETs-related genes between TCGA and transcriptome RNA microarrays. (B) Forest plots demonstrating the results of the univariate Cox regression analysis between NETs-related lncRNA expression and overall survival (OS). (C) Heatmap revealing the NETs-related lncRNAs that were associated with OS by univariate Cox regression analysis in NSCLC patients and healthy people. (D) The coexpression network between 12 NETs-related lncRNAs and prognostic DEGs. Red indicates NETs-related lncRNA, and the purple indicates prognostic DEGs. (E) Sankey diagram showing the relationships among 12 NETs-related lncRNAs, prognostic DEGs and risk types.