Research Paper Volume 13, Issue 14 pp 18442—18463

An interactive nomogram based on clinical and molecular signatures to predict prognosis in multiple myeloma patients

Effects of hub genes on survival outcome of MM patients of GSE24080. (A) Forest plot of multivariate Cox regression analysis for fifteen genes. FAM72A, AURKA, and NUF2 were significantly associated with survival in multiple myeloma patients (pB) Kaplan-Meier analysis of FAM72A, AURKA and NUF2 to predict patient survival. MM patients with the high and low expression levels of three genes were divided into two groups according to the cut-off value of medium expression levels. p-value of the Log-rank test less than 0.05 was considered as a statistical difference.

Figure 5. Effects of hub genes on survival outcome of MM patients of GSE24080. (A) Forest plot of multivariate Cox regression analysis for fifteen genes. FAM72A, AURKA, and NUF2 were significantly associated with survival in multiple myeloma patients (p<0.1). (B) Kaplan-Meier analysis of FAM72A, AURKA and NUF2 to predict patient survival. MM patients with the high and low expression levels of three genes were divided into two groups according to the cut-off value of medium expression levels. p-value of the Log-rank test less than 0.05 was considered as a statistical difference.