Research Paper Advance Articles

Fibroblastic galectin-1-fostered invasion and metastasis are mediated by TGF-β1-induced epithelial-mesenchymal transition in gastric cancer

GAL-1/LGALS1 promotes EMT in GC, and EMT promotes lymph node metastasis of GC. (A) Representative images of GCT without EMT. (B) Representative images of GCT with EMT. (C) GAL-1/LGALS1 significantly promoted EMT in GC (P D) GC with EMT was more prone to lymph node metastasis (P E, F) Representative images of GC cells with or without EMT in metastatic lymph nodes.

Figure 3. GAL-1/LGALS1 promotes EMT in GC, and EMT promotes lymph node metastasis of GC. (A) Representative images of GCT without EMT. (B) Representative images of GCT with EMT. (C) GAL-1/LGALS1 significantly promoted EMT in GC (P < 0.05). (D) GC with EMT was more prone to lymph node metastasis (P < 0.05). (E, F) Representative images of GC cells with or without EMT in metastatic lymph nodes.