Research Paper Volume 13, Issue 14 pp 18482—18497

ZC3HAV1 promotes the proliferation and metastasis via regulating KRAS in pancreatic cancer

After down-regulating KRAS, the promotion roles of ZC3HAV1 played in the proliferation and invasion of PC cells was weakened. (A, B) CCK8 assays were employed to find out the proliferation ability of every group. (C–E) Performed transwell assay in order to examine the invasion ability of each group. (F) The related expression of proteins of proliferation (CDK2) and EMT (N-cadherin) was analyzed by Western blotting. Data appeared to be mean ± SD, *PP

Figure 6. After down-regulating KRAS, the promotion roles of ZC3HAV1 played in the proliferation and invasion of PC cells was weakened. (A, B) CCK8 assays were employed to find out the proliferation ability of every group. (CE) Performed transwell assay in order to examine the invasion ability of each group. (F) The related expression of proteins of proliferation (CDK2) and EMT (N-cadherin) was analyzed by Western blotting. Data appeared to be mean ± SD, *P< 0.05, **P< 0.01.