Research Paper Volume 13, Issue 14 pp 18586—18605

Circular RNA circSP3 promotes hepatocellular carcinoma growth by sponging microRNA-198 and upregulating cyclin-dependent kinase 4

CircSP3 induced HCC cell migration and invasion in vitro. (A, B) Cell migration and invasion were assessed with Transwell assays in Hep-3B cells infected with circSP3 or NC plasmids. (C, D). Transwell assays were carried out to assess cell migration and invasion when circSP3 was downregulated in Huh-7 cells. **p

Figure 5. CircSP3 induced HCC cell migration and invasion in vitro. (A, B) Cell migration and invasion were assessed with Transwell assays in Hep-3B cells infected with circSP3 or NC plasmids. (C, D). Transwell assays were carried out to assess cell migration and invasion when circSP3 was downregulated in Huh-7 cells. **p<0.01.