Research Paper Volume 13, Issue 14 pp 18689—18700

Catalpol enhanced physical exercise-mediated brain functional improvement in post-traumatic stress disorder model via promoting adult hippocampal neurogenesis

Combination of catalpol promoted the effects of treadmill to reduce PTSD associated depressive and anxiety behaviors. (A, B) Mobility time of different	groups in FST and TST. (C) Time of the mice for staying in the center region in OFT. (D) Time of the mice for staying in the open arm during EPM. One-way ANOVA, ***p #p ###p +p ++p

Figure 2. Combination of catalpol promoted the effects of treadmill to reduce PTSD associated depressive and anxiety behaviors. (A, B) Mobility time of different groups in FST and TST. (C) Time of the mice for staying in the center region in OFT. (D) Time of the mice for staying in the open arm during EPM. One-way ANOVA, ***p < 0.001 vs. control; #p < 0.05, ###p < 0.001 vs. PTSD; +p < 0.05, ++p < 0.01 vs. exercise treatment group.