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Identification of prognostic long non-coding RNA signature with potential drugs in hepatocellular carcinoma

Spearman’s correlation analysis and differential drug response analysis of 7 CTRP-derived compounds; (A) and 7 PRISM-derived compounds (B) with OS-classifier; (C) and 3 PRISM-derived compounds; (D) with OS-classifier. Note that lower values on the y-axis of boxplots imply greater drug sensitivity. (E) Heatmap showing each compound (perturbagen) from the CMap dataset that shares mechanisms of action (rows) and sorted by descending number of compound with shared mechanisms of action.

Figure 8. Spearman’s correlation analysis and differential drug response analysis of 7 CTRP-derived compounds; (A) and 7 PRISM-derived compounds (B) with OS-classifier; (C) and 3 PRISM-derived compounds; (D) with OS-classifier. Note that lower values on the y-axis of boxplots imply greater drug sensitivity. (E) Heatmap showing each compound (perturbagen) from the CMap dataset that shares mechanisms of action (rows) and sorted by descending number of compound with shared mechanisms of action.