Research Paper Volume 13, Issue 15 pp 19352—19374

Identification of immune-related genes that predict prognosis and risk of bladder cancer: bioinformatics analysis of TCGA database

Significant modular analysis and functional enrichment analysis based on the PPI network. (A) Construction of a PPI network using a total of 51 prognosis-associated DEIRGs. (B) The most significant module subgroup of the hub genes, identified by MCODE plug-in, contains ten genes. (C) Module 2 contains ten hub genes. (D) Module 3 contains four hub genes. (E) Module 4 contains three hub genes. (F) Functional enrichment analysis of the 27 hub genes in the PPI network.

Figure 4. Significant modular analysis and functional enrichment analysis based on the PPI network. (A) Construction of a PPI network using a total of 51 prognosis-associated DEIRGs. (B) The most significant module subgroup of the hub genes, identified by MCODE plug-in, contains ten genes. (C) Module 2 contains ten hub genes. (D) Module 3 contains four hub genes. (E) Module 4 contains three hub genes. (F) Functional enrichment analysis of the 27 hub genes in the PPI network.