Research Paper Volume 13, Issue 16 pp 20164—20178

Identification of 4-methylation driven genes based prognostic signature in thyroid cancer: an integrative analysis based on the methylmix algorithm

Validation of constructed prognostic signature. (A) The methylation level was detected by qMSP. (B) The protein level was detected by IHC. (C) The Kaplan-Meier plots of the ALDOC, C14orf62, PTPRC. (D) The Kaplan-Meier plot of the prognostic signature based on the median of the risk score in the validation set. (E) The ROC curve for assessing the prediction value of the signature in the validation set.

Figure 4. Validation of constructed prognostic signature. (A) The methylation level was detected by qMSP. (B) The protein level was detected by IHC. (C) The Kaplan-Meier plots of the ALDOC, C14orf62, PTPRC. (D) The Kaplan-Meier plot of the prognostic signature based on the median of the risk score in the validation set. (E) The ROC curve for assessing the prediction value of the signature in the validation set.