Research Paper Volume 13, Issue 14 pp 19048—19063

Combined treatment with C16 peptide and angiopoietin-1 confers neuroprotection and reduces inflammation in 3-nitropropionic acid-induced dystonia mice


Figure 8. Treatment with C16+Ang-l can alleviate 3-NP-induced neuronal loss. Immunofluorescence staining in the (AC) corpus striatum and (DF) nigra substance (white box) at magnification ×100). (GI) The same area of the nigra substance at ×200. (J) Semi-quantitative profiles of IC3 (an autophagy marker) in the control, 3-NP, and 3-NP+C16+Ang-1 groups. Scale bar = 100 μm. aP < 0.05 versus control; bP < 0.05 versus 3-NP-treated mice.