Research Paper Volume 13, Issue 15 pp 19510—19528

UHPLC-MS-based metabolomics and chemoinformatics study reveals the neuroprotective effect and chemical characteristic in Parkinson’s disease mice after oral administration of Wen-Shen-Yang-Gan decoction


Figure 2. Effects of WSYGD on behavioral test of PD chronic model mice. In the pole test, (A) refers to the turning time and (B) refers to the total time; (C) refers to the retention time in the rotarod test. Control: blank group; Model: rotenone-intoxicated group; WSYGD-H: high dosage group; WSYGD-M: medium dosage group; WSYGD-L: Low dosage group; Sinemet: positive control. ***p<0.001 vs. Control; #p<0.05,##p<0.01, ###p<0.001 vs. Model.