Figure 5. AC136007.2 reduces cerebral infarction, brain edema, and brain cell death after MCAO in rats. (A) Detection of brain infarction area by TTC staining. (B) TTC-based quantification of cerebral infarction (as percentage of the whole hemisphere). **p<0.01 versus I/R (MCAO) group; n=6. (C) Cerebral water content measurements. **p<0.01 versus I/R group; n=6. (D) TUNEL staining assessment of apoptosis in brain sections. **p<0.01 versus sham group; ## p<0.01 versus I/R group; n=6.