Research Paper Volume 13, Issue 15 pp 19587—19597

LncRNA AC136007.2 alleviates cerebral ischemic-reperfusion injury by suppressing autophagy

AC136007.2 inhibits IS-induced autophagy by inactivating AMPK-mTOR signaling. (A) Brain expression of LC3 I/II, Beclin 1, p-AMPK, and p-mTOR was evaluated by western blotting. (B–E) Quantification of western blotting results. Expression data were normalized to β-actin. **p## p

Figure 6. AC136007.2 inhibits IS-induced autophagy by inactivating AMPK-mTOR signaling. (A) Brain expression of LC3 I/II, Beclin 1, p-AMPK, and p-mTOR was evaluated by western blotting. (BE) Quantification of western blotting results. Expression data were normalized to β-actin. **p<0.01 versus sham group; ## p<0.01 versus I/R group; n=6.