Figure 8. Effect of Grape skin extract (GSE) on (A) dopamine, (B) noradrenaline, (C) GABA, and (D) glutamate levels in the cerebral cortex of SAMP8. SAMP8 mice were orally administered with 50 mg/kg GSE for 30 days. These neurotransmitters levels were determined by ELISA kit. Each value is presented as mean ± SD. ** P < 0.01 compared with SAMP8+Water by one-way ANOVA.