Research Paper Volume 13, Issue 15 pp 19643—19656

The protective effect of allicin on myocardial ischemia-reperfusion by inhibition of Ca2+ overload-induced cardiomyocyte apoptosis via the PI3K/GRK2/PLC-γ/IP3R signaling pathway

Allicin improved cardiac function in mice after myocardial IR injury. (A) Ultrasound imaging of mice in the control group, model group, and allicin group. (B) The LVEF, LVAW; d, LVAW; s LVDI; d and LVID; s of mice in each group. Data are presented as mean ± SD. **P ##P

Figure 1. Allicin improved cardiac function in mice after myocardial IR injury. (A) Ultrasound imaging of mice in the control group, model group, and allicin group. (B) The LVEF, LVAW; d, LVAW; s LVDI; d and LVID; s of mice in each group. Data are presented as mean ± SD. **P < 0.05 model vs. allicin group; ##P < 0.05 model vs. control group. LVAW;d, left ventricular anterolateral wall diameter. LVEF, left ventricular ejection fraction; LVID;d, left ventricular internal diastolic diameter.