Research Paper Volume 13, Issue 15 pp 19822—19834

Circular RNA ZNF609 drives tumor progression by regulating the miR-138-5p/SIRT7 axis in melanoma

CircZNF609 enhances invasion and migration of melanoma cells. (A–D) The A375 and SK-MEL-28 cells were treated with the circZNF609 shRNA or control shRNA. (A and B) The cell migration and invasion were tested by transwell assays in the cells. (C and D) The migration and invasion were analyzed by wound healing assays in the cells. The wound healing proportion was shown. Data are presented as mean ± SD. Statistic significant differences were indicated: *P **P

Figure 2. CircZNF609 enhances invasion and migration of melanoma cells. (AD) The A375 and SK-MEL-28 cells were treated with the circZNF609 shRNA or control shRNA. (A and B) The cell migration and invasion were tested by transwell assays in the cells. (C and D) The migration and invasion were analyzed by wound healing assays in the cells. The wound healing proportion was shown. Data are presented as mean ± SD. Statistic significant differences were indicated: *P < 0.05, **P < 0.01.