Research Paper Volume 13, Issue 15 pp 19165—19185

Endothelium-specific deletion of amyloid-β precursor protein exacerbates endothelial dysfunction induced by aging

Protein expressions of COX1 (A) and COX2 (B) in the aortas of wild-type (WT) littermates and eAPP−/− mice. Western blot results are the relative densitometry compared with β-actin protein (n=10 per group for COX1 and n=8 per group for COX2). All results are representing box plots with whiskers showing the median, 25th to 75th percentiles, and min-max range. * P

Figure 5. Protein expressions of COX1 (A) and COX2 (B) in the aortas of wild-type (WT) littermates and eAPP−/− mice. Western blot results are the relative densitometry compared with β-actin protein (n=10 per group for COX1 and n=8 per group for COX2). All results are representing box plots with whiskers showing the median, 25th to 75th percentiles, and min-max range. * P<0.05 versus young mice of same strain; † P<0.05 versus age-matched WT littermates (two-way ANOVA followed by Tukey’s HSD test).