Research Paper Volume 13, Issue 16 pp 20246—20257

Identification of effective natural PIK3CA H1047R inhibitors by computational study

Molecular structure of PIK3CA H1047R with the highlighted 1047Arg. (A) The initial molecular structure. (B) Structure after binding area surface was added. Blue represents positive charge and red represents negative charge. (C) The molecular structure of PIK3CA H1047R with wortmannin. (D) The molecular structure of PIK3CA H1047R with PKI-402.

Figure 1. Molecular structure of PIK3CA H1047R with the highlighted 1047Arg. (A) The initial molecular structure. (B) Structure after binding area surface was added. Blue represents positive charge and red represents negative charge. (C) The molecular structure of PIK3CA H1047R with wortmannin. (D) The molecular structure of PIK3CA H1047R with PKI-402.