Research Paper Volume 13, Issue 16 pp 20246—20257

Identification of effective natural PIK3CA H1047R inhibitors by computational study

Schematic representation showing interactions between ligands and 3HHM. The binding area surface was added. Blue represents positive charge and red represents negative charge. Ligands are shown in sticks, with the structure around the ligand–receptor junction shown in thinner sticks. (A) ZINC000004098448–3HHM complex. (B) ZINC000014715656–3HHM complex.

Figure 5. Schematic representation showing interactions between ligands and 3HHM. The binding area surface was added. Blue represents positive charge and red represents negative charge. Ligands are shown in sticks, with the structure around the ligand–receptor junction shown in thinner sticks. (A) ZINC000004098448–3HHM complex. (B) ZINC000014715656–3HHM complex.