Research Paper Volume 13, Issue 16 pp 20372—20382

Circular RNA circRHOT1 contributes to pathogenesis of non-small cell lung cancer by epigenetically enhancing C-MYC expression through recruiting KAT5

The silencing of circRHOT1 attenuates NSCLC cell proliferation in vitro. (A–F) The A549 and H1299 cells were treated with control siRNA or circRHOT1 siRNA. (A and B) The cell viability was analyzed by MTT assays. (C and D) The cell proliferation was detected by colony formation assays. (E and F) The cell survival was detected by Edu assays. mean ± SD, **P

Figure 2. The silencing of circRHOT1 attenuates NSCLC cell proliferation in vitro. (AF) The A549 and H1299 cells were treated with control siRNA or circRHOT1 siRNA. (A and B) The cell viability was analyzed by MTT assays. (C and D) The cell proliferation was detected by colony formation assays. (E and F) The cell survival was detected by Edu assays. mean ± SD, **P < 0.01.