COVID-19 Research Paper Volume 13, Issue 17 pp 20886—20895

The potential role of abnormal angiotensin-converting enzyme 2 expression correlated with immune infiltration after SARS-CoV-2 infection in the prognosis of breast cancer

Correlation between ACE2 expression and immune infiltration in different subtypes of breast cancer. In basal-like breast cancer, ACE2 expression level was positively correlated with neutrophil. While in luminal subtype of breast cancer, the ACE2 expression was strongly positively correlated with the immune infiltration level of CD8+ T cell, CD4+ T cell and neutrophil.

Figure 3. Correlation between ACE2 expression and immune infiltration in different subtypes of breast cancer. In basal-like breast cancer, ACE2 expression level was positively correlated with neutrophil. While in luminal subtype of breast cancer, the ACE2 expression was strongly positively correlated with the immune infiltration level of CD8+ T cell, CD4+ T cell and neutrophil.