Research Paper Volume 13, Issue 16 pp 20552—20568

Mediation of circ_RPPH1 on miR-146b-3p/E2F2 pathway to hinder the growth and metastasis of breast carcinoma cells


Figure 1. Expression of circ_RPPH1 in BC. (A) limma package analysis of differential circRNA volcanic map in GSE101123 chip. (B) Visualizing of differential circRNA heat map by pheatmap package. (C) qRT-PCR was used to detect the relative expression of circ_RPPH1 in BC patients. (D) The relative expression of circ_RPPH1 in BC cell lines was detected by qRT-PCR. (E) The sequence of circ_RPPH1 in circBase (upper part) is consistent with that in Sanger sequencing (lower part). *indicates P < 0.05; **indicates P < 0.01; ***indicates P < 0.001.