Research Paper Volume 13, Issue 16 pp 20050—20080

Effects of Siberian fir terpenes extract Abisil on antioxidant activity, autophagy, transcriptome and proteome of human fibroblasts

The interaction network of protein products encoded by top 200 genes downregulated after Abisil treatment, according to RNA-Seq data (5 μg/ml; MRC5-SV40 cell line). The width of the connecting lines indicates the confidence level of protein interaction (best – mentions in curated databases, experimental data for human; worst – found interacting putative homologs in other organisms).

Figure 14. The interaction network of protein products encoded by top 200 genes downregulated after Abisil treatment, according to RNA-Seq data (5 μg/ml; MRC5-SV40 cell line). The width of the connecting lines indicates the confidence level of protein interaction (best – mentions in curated databases, experimental data for human; worst – found interacting putative homologs in other organisms).