Research Paper Volume 13, Issue 17 pp 21309—21324

Activation of the gut microbiota-kynurenine-liver axis contributes to the development of nonalcoholic hepatic steatosis in nondiabetic adults

Fecal microbiota transplantation (FMT) findings. (A) Histopathological examination of liver tissue in GF mice colonized with gut microbiota from healthy controls or NHS patients (Oil Red O staining). (B) L-tryptophan and kynurenine quantification by UPLC-MS/MS. Data are mean ± SE; h: control group; z: NHS group; *P

Figure 5. Fecal microbiota transplantation (FMT) findings. (A) Histopathological examination of liver tissue in GF mice colonized with gut microbiota from healthy controls or NHS patients (Oil Red O staining). (B) L-tryptophan and kynurenine quantification by UPLC-MS/MS. Data are mean ± SE; h: control group; z: NHS group; *P < 0.05.