Research Paper Volume 13, Issue 18 pp 22134—22147

Rutin inhibited the advanced glycation end products-stimulated inflammatory response and extra-cellular matrix degeneration via targeting TRAF-6 and BCL-2 proteins in mouse model of osteoarthritis

Rutin showed potential binding with TRAF-6 and BCL-2 proteins. Docking study was done and the surface solid pose showed potential binding of Rutin with TRAF-6 and BCL-2. The Ligand (Rutin) was majorly encapsulated in both the protein structures.

Figure 6. Rutin showed potential binding with TRAF-6 and BCL-2 proteins. Docking study was done and the surface solid pose showed potential binding of Rutin with TRAF-6 and BCL-2. The Ligand (Rutin) was majorly encapsulated in both the protein structures.