Research Paper Volume 13, Issue 16 pp 20836—20852

Heparanase is a novel biomarker for immune infiltration and prognosis in breast cancer

Kaplan–Meier survival curves comparing high and low HPSE expression in different cancer types in GEIPA (A–D) and Kaplan–Meier plotter (E–J). (A, B) Survival curves of DFS and OS in BLCA. (C, D) Survival curves of DFS and OS in BRCA. (E–H) Survival curves of RFS, DMFS, PPS and OS in BRCA. (I, J) Survival curves of PPS and OS in STAD. Bladder urothelial carcinoma (BLCA); breast invasive carcinoma (BRCA); disease-free survival (DFS); distant metastasis-free survival (DMFS); disease-specific survival (DSS); heparanase (HPSE); Gene Expression Profiling Interactive Analysis (GEPIA); overall survival (OS); post progression survival (PPS); relapse-free survival (RFS); stomach adenocarcinoma (STAD).

Figure 2. Kaplan–Meier survival curves comparing high and low HPSE expression in different cancer types in GEIPA (AD) and Kaplan–Meier plotter (EJ). (A, B) Survival curves of DFS and OS in BLCA. (C, D) Survival curves of DFS and OS in BRCA. (EH) Survival curves of RFS, DMFS, PPS and OS in BRCA. (I, J) Survival curves of PPS and OS in STAD. Bladder urothelial carcinoma (BLCA); breast invasive carcinoma (BRCA); disease-free survival (DFS); distant metastasis-free survival (DMFS); disease-specific survival (DSS); heparanase (HPSE); Gene Expression Profiling Interactive Analysis (GEPIA); overall survival (OS); post progression survival (PPS); relapse-free survival (RFS); stomach adenocarcinoma (STAD).