Research Paper Volume 13, Issue 16 pp 20836—20852

Heparanase is a novel biomarker for immune infiltration and prognosis in breast cancer

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Figure 5. HPSE expression between MDA-MB-231-HPSE and MDA-MB-231-mock cells (A). HPSE expression correlates with IL-10 induced M2 macrophage polarization in a mouse breast tumor model: IHC staining of (B) CD163, (C) VSIG4, and (D) IL-10.