COVID-19 Research Paper Volume 13, Issue 17 pp 20906—20914

High-dose vitamin C ameliorates cardiac injury in COVID-19 pandemic: a retrospective cohort study


Figure 3. Changes in inflammatory markers levels from baseline to day 21 during hospitalization. The levels of high-sensitivity C-reactive protein (hs-CRP, A), Interleukin-6 (IL-6, B), IL-8 (C), and tumor necrosis factor-α (TNF-α, D) at day 21 during hospitalization in patients administered with high-dose intravenous vitamin C (HIVC, n = 51) significantly decreased compared with those receiving symptomatic supportive treatments alone (n = 62). In addition, changes of the inflammatory markers levels displayed a tendency of significant decrease at day 21 during hospitalization related to baseline in patients underwent HIVC therapy.