Research Paper Volume 13, Issue 17 pp 21642—21658

Astrocyte-derived exosomes protect hippocampal neurons after traumatic brain injury by suppressing mitochondrial oxidative stress and apoptosis

Characterization of AS-Exosomes. (A) Representative transmission electron microscopy (TEM) image show exosomes generated by primary astrocytes. (B) Western blot analysis shows expression levels of exosomal biomarkers such as CD9, CD63, CD81, HSP90B1, and GM130 in astrocyte-derived exosomes (AS-Exo) and astrocyte supernatant. (C) Particle size analysis of AS-Exo. (D) The identification of astrocytes and AS-Exo.

Figure 1. Characterization of AS-Exosomes. (A) Representative transmission electron microscopy (TEM) image show exosomes generated by primary astrocytes. (B) Western blot analysis shows expression levels of exosomal biomarkers such as CD9, CD63, CD81, HSP90B1, and GM130 in astrocyte-derived exosomes (AS-Exo) and astrocyte supernatant. (C) Particle size analysis of AS-Exo. (D) The identification of astrocytes and AS-Exo.