Research Paper Volume 13, Issue 17 pp 21758—21777

The upregulated expression of RFC4 and GMPS mediated by DNA copy number alteration is associated with the early diagnosis and immune escape of ESCC based on a bioinformatic analysis

Upregulated RFC4 and GMPS are associated with the early diagnosis of esophageal carcinoma and may be the biomarkers for the early diagnosis of esophageal carcinoma. (A, B) Expression of RFC4 in patients with esophageal carcinoma based on the stage and nodal metastasis. (C, D) Expression of GMPS in patients with esophageal carcinoma based on the stage and nodal metastasis. (E) Receiver operating characteristic (ROC) curve analysis of RFC4 and GMPS in esophageal carcinoma (n = 173). (F) Receiver operating characteristic (ROC) curve analysis of RFC4 and GMPS in ESCC (n = 46). *p **p ***p

Figure 6. Upregulated RFC4 and GMPS are associated with the early diagnosis of esophageal carcinoma and may be the biomarkers for the early diagnosis of esophageal carcinoma. (A, B) Expression of RFC4 in patients with esophageal carcinoma based on the stage and nodal metastasis. (C, D) Expression of GMPS in patients with esophageal carcinoma based on the stage and nodal metastasis. (E) Receiver operating characteristic (ROC) curve analysis of RFC4 and GMPS in esophageal carcinoma (n = 173). (F) Receiver operating characteristic (ROC) curve analysis of RFC4 and GMPS in ESCC (n = 46). *p < 0.05, **p < 0.01, ***p < 0.001.