The upregulated expression of RFC4 and GMPS mediated by DNA copy number alteration is associated with the early diagnosis and immune escape of ESCC based on a bioinformatic analysis

Jing Wang; Fei-Fei Luo; Tie-Jun Huang; Yan Mei; Li-Xia Peng; Chao-Nan Qian; Bi-Jun Huang

doi:doi:10.18632/aging.203520

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Research Paper Volume 13, Issue 17 pp 21758—21777

The upregulated expression of RFC4 and GMPS mediated by DNA copy number alteration is associated with the early diagnosis and immune escape of ESCC based on a bioinformatic analysis

Figure 7. Upregulated RFC4 and GMPS levels may be mediated by DNA copy number alterations in ESCC. (A) Genetic alteration analysis of RFC4 and GMPS by cBioPortal. (B, D) Putative copy number alterations of RFC4 and GMPS in esophageal cancer. (C, E) Putative copy number alteration analysis of RFC4 and GMPS based on different T, N, and M stages. (F, G) DNA copy number of RFC4 and GMPS in Hu Esophagus 2. ^*p < 0.05, ^**p < 0.01, ^***p < 0.001.