Research Paper Volume 13, Issue 18 pp 22208—22231

Involvement of c-Myc in low dose radiation-induced senescence enhanced migration and invasion of unirradiated cancer cells

Expression of c-Myc and K-Ras in LDR induced senescence. (A) Western blot analysis for detecting the expression of c-Myc, K-Ras, p53, p16 and p27 in cells exposed to LDR. (B and C) qPCR was used for detection of c-Myc mRNA levels in H1299 cells and WI-38 cells after ionizing radiation, respectively. (D and E) The expression of K-Ras mRNA in H1299 cells and WI-38 cells exposed to ionizing radiation, respectively. *p

Figure 3. Expression of c-Myc and K-Ras in LDR induced senescence. (A) Western blot analysis for detecting the expression of c-Myc, K-Ras, p53, p16 and p27 in cells exposed to LDR. (B and C) qPCR was used for detection of c-Myc mRNA levels in H1299 cells and WI-38 cells after ionizing radiation, respectively. (D and E) The expression of K-Ras mRNA in H1299 cells and WI-38 cells exposed to ionizing radiation, respectively. *p < 0.05.