Research Paper Volume 13, Issue 18 pp 22208—22231

Involvement of c-Myc in low dose radiation-induced senescence enhanced migration and invasion of unirradiated cancer cells

Cytokine array analysis of CM from cells treated with LDR with or without the presence of c-Myc inhibitor. (A) The cytokine array was used to detect the cytokines released in CM of LDR (0.5Gy) treated H1299 cells with or without c-Myc inhibitor (Myc IB, 50 μM). Densitometric quantification of 42 cytokines detected in the cytokine array. Data represent the means of duplicated dots. (B) Effects of CM from cells treated with LDR with or without the presence of c-Myc inhibitor on the expression of MCP1, MCP-2, TNF-α and TNF-β. *p

Figure 6. Cytokine array analysis of CM from cells treated with LDR with or without the presence of c-Myc inhibitor. (A) The cytokine array was used to detect the cytokines released in CM of LDR (0.5Gy) treated H1299 cells with or without c-Myc inhibitor (Myc IB, 50 μM). Densitometric quantification of 42 cytokines detected in the cytokine array. Data represent the means of duplicated dots. (B) Effects of CM from cells treated with LDR with or without the presence of c-Myc inhibitor on the expression of MCP1, MCP-2, TNF-α and TNF-β. *p < 0.05.