Research Paper Volume 13, Issue 18 pp 22298—22314

AKR1B10 inhibits the proliferation and migration of gastric cancer via regulating epithelial-mesenchymal transition

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Figure 1. Expression of AKR1B10 in gastric cancer tissues. (A) Representative immunohistochemistry images showing in situ AKR1B10 expression in gastric cancer (GC) and normal tissues (scale bar = 100 μm). (BD) IHC scores of AKR1B10 in (B) GC vs normal tissues, (C) tumors with and without lymph node invasion, and (D) TNM stage I–II vs III–IV. (EG) overall survival analysis of (E) AKR1B10pos vs AKRiB10neg GC patients, and in subgroups overall survival analysis of TNM stage I–II (F) and III–IV (G). LNM, Lymph node metastasis.