Research Paper Volume 13, Issue 18 pp 22361—22374

Identification of clinical trait-related small RNA biomarkers with weighted gene co-expression network analysis for personalized medicine in endocervical adenocarcinoma

Construction of weighted gene co-expression network by analyzing of miRNA. (A) Sample dendrogram and clinical variable heatmap based on miRNA. (B) Determination of network topology from different soft-threshold powers. (C) Check scale-free topology. (D) Clustering dendrograms of identified co-expressed miRNAs in modules. (E) Heatmaps of the correlation between eigengene and clinical traits based on miRNA.

Figure 2. Construction of weighted gene co-expression network by analyzing of miRNA. (A) Sample dendrogram and clinical variable heatmap based on miRNA. (B) Determination of network topology from different soft-threshold powers. (C) Check scale-free topology. (D) Clustering dendrograms of identified co-expressed miRNAs in modules. (E) Heatmaps of the correlation between eigengene and clinical traits based on miRNA.