Research Paper Volume 13, Issue 18 pp 22375—22389

A new mechanism of POCD caused by sevoflurane in mice: cognitive impairment induced by cross-dysfunction of iron and glucose metabolism

Sev decreased the cognitive function of elder mice. The mice were treated with Sev as described in the Materials and Methods section. The cognitive function was detected by the MWM test. The results were calculated as the escape latency (sec.) and platform crossing time ± SD (n = 15). (A, C). (B) Shows the typical movement locus. *P

Figure 1. Sev decreased the cognitive function of elder mice. The mice were treated with Sev as described in the Materials and Methods section. The cognitive function was detected by the MWM test. The results were calculated as the escape latency (sec.) and platform crossing time ± SD (n = 15). (A, C). (B) Shows the typical movement locus. *P < 0.05 compared with the control group by one-way ANOVA.