Research Paper Volume 13, Issue 18 pp 22432—22443

Circular RNA Foxo3 enhances progression of ovarian carcinoma cells

Upregulation of Foxo3 promotes OC cell proliferation. (A) The expression of Foxo3 in OC and control cells. (B) Visualization of lentivirus transfection in SKOV3 cells, as observed by fluorescence microscope. Scale bar = 75 μm. (C) Transfection efficiency in Foxo3-knockdown or Foxo3-overexpressing SKOV3 cells. (D) Cell proliferation of SKOV3 cells with Foxo3 knockdown or overexpressing, as determined by CCK-8 assay. Data were expressed as means ± standard deviation. For each treatment, three replicates were used. **p ***p

Figure 1. Upregulation of Foxo3 promotes OC cell proliferation. (A) The expression of Foxo3 in OC and control cells. (B) Visualization of lentivirus transfection in SKOV3 cells, as observed by fluorescence microscope. Scale bar = 75 μm. (C) Transfection efficiency in Foxo3-knockdown or Foxo3-overexpressing SKOV3 cells. (D) Cell proliferation of SKOV3 cells with Foxo3 knockdown or overexpressing, as determined by CCK-8 assay. Data were expressed as means ± standard deviation. For each treatment, three replicates were used. **p < 0.01, ***p < 0.001.